Angiogenesis is tightly regulated through the binding of vascular endothelial growth factors (VEGFs) to their receptors (VEGFRs). In this context. we showed that human VEGFR1 domain 2 crystallizes in the presence of Zn2+. Co2+ or Cu2+ as a dimer that forms via metal-ion interactions and interlocked hydrophobic surfaces. https://megavitamines.shop/product-category/carb-blocker/