BackgroundDifferent histone post-translational modifications (PTMs) are crucial in the regulation of chromatin. including methylations of H3 at Lysine 4 by the MLL complex. A relevant issue is how this is causally correlated to the binding of specific transcription factors (TFs) in regulatory regions. NF-Y is a TF that regulates 30% of mammalian promoters containing the widespread CCA... https://www.roneverhart.com/Verragio-Paradiso-Round-Diamond-Engagement-Ring-Setting-0-55-CTW-p5464/