Opioid Antagonists, like naloxone, are precise antidotes to respiratory despair ensuing from opioid overdose. For clinically sizeable respiratory or circulatory depression secondary to acetaminophen and codeine overdose, administer an opioid antagonist. These effects seem to boost with the duration of treatment. The medical significance of such findings just isn't identified. https://codeine.store/codeine-for-cough/